Atypical ductal hyperplasia ADH is not a form of breast cancer. Rather, it is a marker for women who may have a risk factor for developing breast cancer in the future. If you have a biopsy that shows atypical ductal hyperplasia in one of your breasts, your doctor will want to follow your breast health very carefully. Armed with this knowledge, you will want to choose a comprehensive breast center.
Hyperplasia of the Breast (Ductal or Lobular)
Atypical Ductal Hyperplasia: Cancer Risk, DCIS, and Treatment
The ducts in your breast are lined with two layers of cells. Ductal hyperplasia refers to having more than two layers of cells. With usual ductal hyperplasia, these extra cells look normal. However, these unusual cells are more likely to turn into cancer.
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Topic: Atypical ductal hyperplasia
Atypical ductal hyperplasia ADH is a common diagnosis in the mammographic era and a significant clinical problem with wide variation in diagnosis and treatment. After a diagnosis of ADH on biopsy a proportion are upgraded to carcinoma upon excision; however, the remainder of patients are overtreated. While ADH is considered a non-obligate precursor of invasive carcinoma, the molecular taxonomy remains unknown. Although a few studies have revealed some of the key genomic characteristics of ADH, a clear understanding of the molecular changes associated with breast cancer progression has been limited by inadequately powered studies and low resolution methodology. Complicating factors such as family history, and whether the ADH present in a biopsy is an isolated lesion or part of a greater neoplastic process beyond the limited biopsy material, make accurate interpretation of genomic features and their impact on progression to malignancy a challenging task.
What is hyperplasia? Treatment and follow-up 6. What this means for you. Hyperplasia is a benign not cancer breast condition. Back to top.